Spatial and Temporal Diffusion of House Prices in the UK

This paper provides a method for the analysis of the spatial and temporal diffusion of shocks in a dynamic system. We use changes in real house prices within the UK economy at the level of regions to illustrate its use. Adjustment to shocks involves both a region specific and a spatial effect. Shocks to a dominant region - London - are propagated contemporaneously and spatially to other regions. They in turn impact on other regions with a delay. We allow for lagged effects to echo back to the dominant region. London in turn is influenced by international developments through its link to New York and other financial centers. It is shown that New York house prices have a direct effect on London house prices. We analyse the effect of shocks using generalised spatio-temporal impulse responses. These highlight the diffusion of shocks both over time (as with the conventional impulse responses) and over space.House Prices, Cross Sectional Dependence, Spatial Dependence

In--Flight (K−,pK^-,p) Reactions for the Formation of Kaonic Atoms and Kaonic Nuclei in Green function method

We study theoretically the kaonic atom and kaonic nucleus formations in the in--flight ($K^-,p$) reactions using the Green function method, which is suited to evaluate formation rates both of stable and unstable bound systems. We consider $^{12}$C and $^{16}$O as the targets and calculate the spectra of the ($K^-,p$) reactions. We conclude that a no peak structure due to kaonic nucleus formation is expected in the reaction spectra calculated with the chiral unitary kaon--nucleus optical potential. In the spectra with the phenomenological deep kaon--nucleus potential, we may have possibilities to observe some structures due to kaonic nucleus states. For all cases, we have peaks due to the kaonic atom formations in the reaction spectra.Comment: 10 pages, 9 figures, newly calculated results added, revisions and updated references, to appear in Physical Review

Emergence of noncollinear magnetic ordering in small magnetic clusters: Mnn_n and As@Mnn_n

Using first-principles density functional calculations, we have studied the magnetic ordering in pure Mn$_n$ ($n=2-$10, 13, 15, 19) and As@Mn$_n$ ($n=1-$10) clusters. Although, for both pure and doped manganese clusters, there exists many collinear and noncollinear isomers close in energy, the smaller clusters with $n\leqslant$5 have collinear magnetic ground state and the emergence of noncollinear ground states is seen for $n\geqslant$6 clusters. Due to strong $p-d$ hybridization in As@Mn$_n$ clusters, the binding energy is substantially enhanced and the magnetic moment is reduced compared to the corresponding pure Mn$_n$ clusters.Comment: 10 Pages and 5 Figure

Formation of Deeply Bound Kaonic Atoms in (K^-,N) Reactions

We study theoretically the (K^-,N) reactions for the formation of the deeply bound kaonic atoms, which were predicted to be quasi--stable with narrow widths, using the Green function method. We consider various cases with different target nuclei and energies systematically and find the clear signals in the theoretical spectra for all cases considered in this article. The signals show very interesting structures, such as the $RESONANCE DIP$ instead of the resonance peak. We discuss the origins of the interesting structures and possibilities to get new information on the existence of the kaonic nuclei from the spectra of the atomic state formations.Comment: 11 pages, 9 figure

Structural Insights into Differences in Drug-binding Selectivity between Two Forms of Human α1-Acid Glycoprotein Genetic Variants, the A and F1*S Forms

Human α1-acid glycoprotein (hAGP) in serum functions as a carrier of basic drugs. In most individuals, hAGP exists as a mixture of two genetic variants, the F1*S and A variants, which bind drugs with different selectivities. We prepared a mutant of the A variant, C149R, and showed that its drug-binding properties were indistinguishable from those of the wild type. In this study, we determined the crystal structures of this mutant hAGP alone and complexed with disopyramide (DSP), amitriptyline (AMT), and the nonspecific drug chlorpromazine (CPZ). The crystal structures revealed that the drug-binding pocket on the A variant is located within an eight-stranded β-barrel, similar to that found in the F1*S variant and other lipocalin family proteins. However, the binding region of the A variant is narrower than that of the F1*S variant. In the crystal structures of complexes with DSP and AMT, the two aromatic rings of each drug interact with Phe-49 and Phe-112 at the bottom of the binding pocket. Although the structure of CPZ is similar to those of DSP and AMT, its fused aromatic ring system, which is extended in length by the addition of a chlorine atom, appears to dictate an alternative mode of binding, which explains its nonselective binding to the F1*S and A variant hAGPs. Modeling experiments based on the co-crystal structures suggest that, in complexes of DSP, AMT, or CPZ with the F1*S variant, Phe-114 sterically hinders interactions with DSP and AMT, but not CPZ. © 2011 by The American Society for Biochemistry and Molecular Biology, Inc

Unusual ocean-atmosphere conditions in the tropical Indian Ocean during 1994

The southeastern tropical Indian Ocean (SETIO) was characterized by unusually cold sea surface temperature (SST) and strong northwestward alongshore surface winds during 1994. Using multi-source data sets including ocean model simulation, two key processes are identified for the SETIO cooling. Entrainment cooling produced most of the negative SST anomaly near the coast whereas evaporative cooling dominated the process away from the coast. Convection was anomalously suppressed over SETIO and the divergence of moist air from the region helped the local evaporative process. This also led to anomalous moisture transports that explain the enhanced convection over the central equatorial Indian Ocean, India and East Asia. The positive feedback between the enhanced and suppressed convection regions in turn helped maintain the surface wind anomalies. These evidences clearly indicate the existence of an ocean-atmosphere coupled phenomenon in the Indian Ocean during 1994

Recent topics of mesic atoms and mesic nuclei -- ϕ\phi mesic nuclei exist ?--

We study $\phi$-meson production in nuclei to investigate the in-medium modification of the $\phi$-meson spectral function at finite density. We consider (${\bar p},\phi$), ($\gamma,p$) and ($\pi^-,n$) reactions to produce a $\phi$-meson inside the nucleus and evaluate the effects of the medium modifications to reaction cross sections. The structures of the bound states, $\phi$-mesic nuclei, are also studied. For strong absorptive interaction cases, we need to know the spectrum shape in a wide energy region to deduce the properties of $\phi$.Comment: Talk given at EXA08, Vienna, September 2008. To be published in the Proceedings, Hyperfine Interactions. 6 pages, 6 figure